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Literature summary for 3.4.24.35 extracted from
- Localization of matrix metalloproteinase (MMP)-9 in lung tissue of a murine model of allergic asthma (2012), Immunol. Invest., 41, 87-96.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| tissue inhibitor of metalloproteinases 1 | TIMP-1 | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P41245 | - |
- |
| Mus musculus C57BL/6 | P41245 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epithelial cell | - |
Mus musculus | - |
| lung | method development and evaluation for immunostaining MMP-9 in mouse lung paraffin-embedded tissue utilizing human ovary as a control, overview. MMP-9 localization in lung tissue of a murine model of allergic asthma induced by chicken ovalbumin. The murine model of allergic asthma consists of a tissue inhibitor of metalloproteinase (TIMP)-1 genetic knockout backcrossed over 10 generations from 129/sv mice on a C57Bl/6 background | Mus musculus | - |
| lymphocyte | - |
Mus musculus | - |
| macrophage | - |
Mus musculus | - |
| monocyte | - |
Mus musculus | - |
| neutrophil | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| gelatinase B | - |
Mus musculus |
| matrix metalloproteinase-9 | - |
Mus musculus |
| MMP-9 | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | administration of MMP-9 specific siRNA to the lungs of sensitized animals would abrogate development of an asthma phenotype, with endpoints of reduced airway hypersensitivity, less inflammation and tissue remodeling, less cellular migration of lymphocytes and eosinophils, and less activation of inflammatory cells, in both BAL fluids and lung tissues | Mus musculus |
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Release 2023.1 (January 2023)
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