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Literature summary for 3.4.24.35 extracted from

  • Musumeci, G.; Magro, G.; Cardile, V.; Coco, M.; Marzagalli, R.; Castrogiovanni, P.; Imbesi, R.; Graziano, A.; Barone, F.; Di Rosa, M.; Castorina, S.; Castorina, A.
    Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme (2015), Cell Tissue Res., 362, 45-60.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
gene MMP-9, quantitative real time PCR expression analysis in glioblastoma Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P14780
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
glioblastoma cell the enzyme is upregulated compared to control brain Homo sapiens
-
additional information quantitative real time PCR enzyme expression analysis and immunohistochemic analysis in glioblastoma, MMP-9 activity is constitutively heightened in tissue samples from primary glioblastoma multiforme, the most common and aggressive malignant primary brain tumor in humans Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
matrix metallopeptidase 9
-
 Homo sapiens
matrix metalloproteinase-9
-
 Homo sapiens
MMP-9
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme act as important oncogenes that improve invasiveness of cancer cells. MMP-9 activity is constitutively heightened in tissue samples from primary glioblastoma multiforme, the most common and aggressive malignant primary brain tumor in humans Homo sapiens