Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
105000 | - |
the molecular mass of recombinant MMP-9 is approximately 105000 Da, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
chondroitin sulfate proteoglycan + H2O | Mus musculus | - |
? | - |
? | |
collagen type IV + H2O | Mus musculus | - |
? | - |
? | |
collagen type V + H2O | Mus musculus | - |
? | - |
? | |
Laminin + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
chondroitin sulfate proteoglycan + H2O | - |
Mus musculus | ? | - |
? | |
collagen type IV + H2O | - |
Mus musculus | ? | - |
? | |
collagen type V + H2O | - |
Mus musculus | ? | - |
? | |
Gelatin + H2O | - |
Mus musculus | ? | - |
? | |
Laminin + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase-9 | - |
Mus musculus |
MMP-9 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | the intracerebroventricular injection of amyloid beta25-35, amyloid beta1-40, and amyloid beta1-42, but not amyloid beta40-1, transiently increases MMP-9 activity and protein expression in the hippocampus, the expression of MMP-9 is increased in both neurons and glial cells in the hippocampus after amyloid beta treatment | up |
General Information | Comment | Organism |
---|---|---|
malfunction | matrix metalloprotease-9 inhibition improves amyloid beta-mediated cognitive impairment and neurotoxicity in mice | Mus musculus |
physiological function | MMP-9 plays a causal role in amyloid beta-induced cognitive impairment and neurotoxicity | Mus musculus |