Literature summary for 3.4.24.35 extracted from

Amaro, S.; Obach, V.; Cervera, A.; Urra, X.; Gomez-Choco, M.; Planas, A.M.; Chamorro, A.
Course of matrix metalloproteinase-9 isoforms after the administration of uric acid in patients with acute stroke: a proof-of-concept study (2009), J. Neurol., 256, 651-656.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
Matrix metalloproteinase 9	-	Homo sapiens
MMP-9	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	active treatment with uric acid (0.5 or 1.0 mg) is associated with reduced levels of active MMP-9 at the end of infusion	down

General Information

General Information	Comment	Organism
physiological function	activated MMP-9 degrades components of the neurovascular unit, mediates blood-brain barrier leakage, and facilitates brain edema and hemorrhage	Homo sapiens

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Release 2023.1 (January 2023)