Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | MMP-9 is a Zn2+-dependent endopeptidase | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
gelatinase B | - |
Mus musculus |
matrix metalloproteinase-9 | - |
Mus musculus |
MMP-9 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | in mice lacking MMP-9 the enhanced COX-1-PGE2 decreases caspase-3 expression and activity leading to impaired apoptosis of inflammatory neutrophils resulting in abnormal accumulation of the cells at the inflammatory focus | Mus musculus |
physiological function | MMP-9 is a key enzyme in neutrophil biology | Mus musculus |