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Literature summary for 3.4.24.35 extracted from

  • Pan, M.H.; Lin, Y.T.; Lin, C.L.; Wei, C.S.; Ho, C.T.; Chen, W.J.
    Suppression of heregulin-beta1/HER2-modulated invasive and aggressive phenotype of breast carcinoma by pterostilbene via inhibition of matrix metalloproteinase-9, p38 kinase cascade and Akt activation (2011), Evid. Based. Complement Alternat. Med., 2011, 562187.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
-
Homo sapiens
MMP-9
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens pterostilbene (i.e. trans-3,5-dimethoxy-4'-hydroxystilbene) down-regulates matrix metalloproteinase-9 activity and inhibits protein and mRNA expression of MMP-9 driven by heregulin-beta1 down
Homo sapiens heregulin-beta1 stimulates MMP-9 secretion and activation via a transcriptional regulation in human breast cancer cells up