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Literature summary for 3.4.24.35 extracted from

  • Lin, C.C.; Kuo, C.T.; Cheng, C.Y.; Wu, C.Y.; Lee, C.W.; Hsieh, H.L.; Lee, I.T.; Yang, C.M.
    IL-1beta promotes A549 cell migration via MAPKs/AP-1- and NF-kappaB-dependent matrix metalloproteinase-9 expression (2009), Cell. Signal., 21, 1652-1662.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
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Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
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Homo sapiens
MMP-9
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the interleukin-1beta-induced MMP-9 gene expression is mediated through the activation of p42/p44 mitogen-activated protein kinase, p38 mitogen-activated protein kinase, and JNK1/2 in A-549 cells. The interleukin-1beta-induced MMP-9 gene expression is also mediated through the translocation of NF-kappaB (p65) into the nucleus and the degradation of IkappaBalpha up