Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.35 extracted from

  • Choi, M.S.; Cho, K.S.; Shin, S.M.; Ko, H.M.; Kwon, K.J.; Shin, C.Y.; Ko, K.H.
    ATP induced microglial cell migration through non-transcriptional activation of matrix metalloproteinase-9 (2010), Arch. Pharm. Res., 33, 257-265.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information ATP non-transcriptionally increases MMP-9 activity by activation of P2Y and PI3K, the increased activity of secreted MMP-9 is due to the increased protein secretion, but not by the increased MMP-9 mRNA and protein expression Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
GM6001 MMP-9-specific inhibitor Mus musculus
SB-3CT MMP-9-specific inhibitor Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BV-2 cell
-
Mus musculus
-
microglial cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
Matrix metalloproteinase 9
-
Mus musculus
MMP-9
-
Mus musculus
Type IV collagen metalloproteinase
-
Mus musculus