Any feedback?
Literature summary for 3.4.24.34 extracted from
- The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition (2001), J. Biol. Chem., 276, 17405-17412.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | design of anticancer or other drugs which should be highly selective for their particular MMP targets | Homo sapiens |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| I-COL 043 | - |
Homo sapiens |  |
| RO200-1770 | - |
Homo sapiens | |
| RO204-1924 | - |
Homo sapiens | |
| RO206-0027 | - |
Homo sapiens | |
| RO206-0032 | - |
Homo sapiens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | zinc endoproteinase | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| M-1855 + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| human neutrophil collagenase | - |
Homo sapiens |
| matrix metalloproteinase | - |
Homo sapiens |
| MMP-8 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
