Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen + H2O | Vibrio sp. | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro | ? | - |
? | |
Collagen + H2O | Hathewaya histolytica | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro | ? | - |
? | |
Collagen + H2O | Vibrio sp. B-30 | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hathewaya histolytica | - |
2-6 different collagenase fractions can be differentiated on the basis of substrate preference | - |
Vibrio sp. | - |
B-30 | - |
Vibrio sp. B-30 | - |
B-30 | - |
Purification (Comment) | Organism |
---|---|
- |
Hathewaya histolytica |
Storage Stability | Organism |
---|---|
-20°C, lyophilized enzyme: 5 years, solutions: several months | Hathewaya histolytica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-phenylazobenzyloxycarbonyl-Pro-Leu-Gly-Pro-Arg + H2O | - |
Hathewaya histolytica | 4-phenylazobenzyloxycarbonyl-Pro-Leu + Gly-Pro-Arg | - |
? | |
Azocoll + H2O | - |
Hathewaya histolytica | Hydrolyzed azocoll | - |
? | |
carbobenzoxy-Gly-Pro-Gly-Gly-Pro-Ala + H2O | - |
Hathewaya histolytica | carbobenzoxy-Gly-Pro-Gly + Gly-Pro-Ala | - |
? | |
carbobenzoxy-Gly-Pro-Leu-Gly-Pro + H2O | - |
Hathewaya histolytica | carbobenzoxy-Gly-Pro-Leu + Gly-Pro | - |
? | |
Collagen + H2O | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form | Vibrio sp. | Hydrolyzed collagen | - |
? | |
Collagen + H2O | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form | Hathewaya histolytica | Hydrolyzed collagen | - |
? | |
Collagen + H2O | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form | Vibrio sp. B-30 | Hydrolyzed collagen | - |
? | |
Collagen + H2O | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro | Vibrio sp. | ? | - |
? | |
Collagen + H2O | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro | Hathewaya histolytica | ? | - |
? | |
Collagen + H2O | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro | Vibrio sp. B-30 | ? | - |
? | |
additional information | other forms with broader specificity isolated from the same source: collagenase B, collagenase II, pseudocollagenase | Vibrio sp. | ? | - |
? | |
additional information | other forms with broader specificity isolated from the same source: collagenase B, collagenase II, pseudocollagenase | Hathewaya histolytica | ? | - |
? | |
additional information | minimum sequence requirement: R-Pro-X-Gly-Pro, Pro can be substituted by Hyp and the first imino group must be blocked, cleavage between X and Gly | Vibrio sp. | ? | - |
? | |
additional information | minimum sequence requirement: R-Pro-X-Gly-Pro, Pro can be substituted by Hyp and the first imino group must be blocked, cleavage between X and Gly | Hathewaya histolytica | ? | - |
? | |
additional information | other forms with broader specificity isolated from the same source: collagenase B, collagenase II, pseudocollagenase | Vibrio sp. B-30 | ? | - |
? | |
additional information | minimum sequence requirement: R-Pro-X-Gly-Pro, Pro can be substituted by Hyp and the first imino group must be blocked, cleavage between X and Gly | Vibrio sp. B-30 | ? | - |
? |