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Literature summary for 3.4.24.25 extracted from

  • Bjornsdottir, B.; Fridjonsson, O.H.; Magnusdottir, S.; Andresdottir, V.; Hreggvidsson, G.O.; Gudmundsdottir, B.K.
    Characterisation of an extracellular vibriolysin of the fish pathogen Moritella viscosa (2008), Vet. Microbiol., 136, 326-334.
    View publication on PubMed
Search for more literature for 3.4.24.25

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline 1 mM, 73% loss of activity Moritella viscosa
EDTA 1 mM, 16% loss of activity Moritella viscosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Moritella viscosa isolated proteinase MvP1 is non-lethal to salmon at concentrations up to 0.22 microg/g fish. It causes considerable tissue necrosis and hemorrhages at the site of injection, and affects cell-cell adhesions in EPC and BF-2 cell lines, but is not highly cytotoxic. The peptidase partially degrades fish IgM heavy chain but is non-hemolytic ?
-
 ?

Organism

Organism UniProt Comment Textmining
Moritella viscosa B5AX16
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification the MvP1 propeptide undergoes both N-terminal and C-terminal processing and different C-terminal processing results in the formation of several active isoforms of the mature peptidase Moritella viscosa

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2020
-
 substrate casein, 30°C Moritella viscosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
casein + H2O
-
 Moritella viscosa ?
-
 ?
Collagen + H2O from lumpfish skin Moritella viscosa ?
-
 ?
Gelatin + H2O
-
 Moritella viscosa ?
-
 ?
additional information isolated proteinase MvP1 is non-lethal to salmon at concentrations up to 0.22 microg/g fish. It causes considerable tissue necrosis and hemorrhages at the site of injection, and affects cell-cell adhesions in EPC and BF-2 cell lines, but is not highly cytotoxic. The peptidase partially degrades fish IgM heavy chain but is non-hemolytic Moritella viscosa ?
-
 ?

Subunits

Subunits Comment Organism
More gene encodes a signal sequence, an N-terminal propeptide, a mature peptidase domain and a C-terminal propeptide Moritella viscosa

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
40
-
-
 Moritella viscosa

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
5
-
 35% residual activity Moritella viscosa

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
50
-
 30 min, 60% residual activity Moritella viscosa