Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | Mus musculus | - |
? | - |
? | |
Gelatin + H2O | Mus musculus BALB/c | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P33434 | gene Mmp2 | - |
Mus musculus BALB/c | P33434 | gene Mmp2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
3T3-F442A cell | - |
Mus musculus | - |
adipose tissue | - |
Mus musculus | - |
embryonic fibroblast | - |
Mus musculus | - |
preadipocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | - |
Mus musculus | ? | - |
? | |
Gelatin + H2O | - |
Mus musculus BALB/c | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MMP-2 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | in de novo formed fat pads, resulting from preadipocytes with Mmp2 knockdown, the expression of aP2, Ppar-gamma and adiponectin is significantly lower, and collagen is more preserved. The fat pad weights as well as size and density of adipocytes or blood vessels are not significantly different from controls, phenotype, overview | Mus musculus |
metabolism | expansion of adipose tissue is dependent on adipogenesis, angiogenesis and extracellular matrix remodeling by the gelatinase subfamily of the matrix metalloproteinases, overview | Mus musculus |
physiological function | the enzyme gelatinase A is involved in adipogenesis, selective modulation of MMP-2 levels affects adipogenesis | Mus musculus |