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Literature summary for 3.4.24.24 extracted from

  • Zhang, R.; Pan, X.; Huang, Z.; Weber, G.F.; Zhang, G.
    Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines (2011), PLoS ONE, 6, e23831.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.24

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-
hepatocellular carcinoma cell
-
 Homo sapiens
-
SMMC-7721 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information gel zymography for activity determination Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
MMP-2
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens inhibition of the SDF-1a/CXCR4 axis downregulates the rhOPN-induced MMP-2 expression and activity down
Homo sapiens expression and activity of MMP-2 is 6fold induced by osteopontin through binding to integrin avb3 and CD44v6 in hepatocellular carcinoma cells SMMC7721 and HepG2 up

General Information

General Information Comment Organism
additional information the SDF-1a/CXCR4 axis is involved in osteopontininduced MMP-2 expression and activity, overview Homo sapiens