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Literature summary for 3.4.24.24 extracted from

  • Wu, M.; Massaeli, H.; Durston, M.; Mesaeli, N.
    Differential expression and activity of matrix metalloproteinase-2 and -9 in the calreticulin deficient cells (2007), Matrix Biol., 26, 463-472.
    View publication on PubMed
Search for more literature for 3.4.24.24

Activating Compound

Activating Compound Comment Organism Structure
additional information a complex formed by MT1-MMP, TIMP-2, and MMP-2 and located at the cell surface, is involved in MMP-2 activation, overview Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
MMP-2 expression analysis in embryonic tissues of wild-type and caireticulin-deficient mice, overview Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information calreticulin-deficient null mice embryos show increased MMP-2 expression and activity, but unaltered TIMP-2 inhibitor levels, the embryos show defects in the heart and body wall, phenotype, overview Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
additional information calreticulin-deficient null mice embryos show increased MMP-2 expression and activity, phosphatidylinositol 3 kinase inhibitor decreases the MMP-2 expression, overview Mus musculus
TIMP-2
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface complex formed by MT1-MMP, TIMP-2 Mus musculus 9986
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Mus musculus
-
heart
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 MMP-2 activity in embryonic tissues of wild-type and caireticulin-deficient mice, overview Mus musculus

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-2
-
 Mus musculus
MMP-2
-
 Mus musculus