Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.24 extracted from

  • Kim, M.M.; Kim, S.K.
    Chitooligosaccharides inhibit activation and expression of matrix metalloproteinase-2 in human dermal fibroblasts (2006), FEBS Lett., 580, 2661-2666.
    View publication on PubMed
Search for more literature for 3.4.24.24

Inhibitors

Inhibitors Comment Organism Structure
chitooligosaccharides inhibit MMP-2 enzyme expression, decrease of the gene expression and transcriptional activity of MMP-2, and catalytic activity in primary dermal fibroblasts, chitooligosaccharides of 3-5 kDa are most effective Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Homo sapiens
-
 ?
-
 ?
additional information Homo sapiens chitooligosaccharides may play an important role in the prevention and treatment of several MMP-2 mediated health problems such as metastasis and wrinkle formation, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast primary dermal Homo sapiens
-
skin
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
 Homo sapiens ?
-
 ?
Gelatin + H2O gelatin zymography Homo sapiens ?
-
 ?
additional information chitooligosaccharides may play an important role in the prevention and treatment of several MMP-2 mediated health problems such as metastasis and wrinkle formation, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-2
-
 Homo sapiens
MMP-2
-
 Homo sapiens