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Literature summary for 3.4.24.24 extracted from

  • Murphy, G.; McAlpine, C.G.; Poll, C.T.; Reynolds, J.J.
    Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen (1985), Biochim. Biophys. Acta, 831, 49-58.
    View publication on PubMed
Search for more literature for 3.4.24.24

Activating Compound

Activating Compound Comment Organism Structure
additional information rapid activation of the zymogen by 4-aminophenylmercuric acetate Oryctolagus cuniculus
additional information trypsin is a poor activator Oryctolagus cuniculus

Inhibitors

Inhibitors Comment Organism Structure
Tissue inhibitor of metalloproteinases
-
 Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Oryctolagus cuniculus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
61000
-
 x * 61000, rabbit, active form, SDS-PAGE under nonreducing conditions Oryctolagus cuniculus
65000
-
 x * 65000, rabbit, latent form, SDS-PAGE under nonreducing conditions Oryctolagus cuniculus
65000
-
 x * 65000, rabbit, active form, SDS-PAGE under reducing conditions Oryctolagus cuniculus
72000
-
 x * 72000, rabbit, latent form, SDS-PAGE under reducing conditions Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
culture medium from calvariae Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen + H2O type IV Oryctolagus cuniculus ?
-
 ?
Collagen + H2O type V Oryctolagus cuniculus ?
-
 ?
Elastin + H2O
-
 Oryctolagus cuniculus ?
-
 ?
Gelatin + H2O
-
 Oryctolagus cuniculus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 65000, rabbit, latent form, SDS-PAGE under nonreducing conditions Oryctolagus cuniculus
? x * 61000, rabbit, active form, SDS-PAGE under nonreducing conditions Oryctolagus cuniculus
? x * 72000, rabbit, latent form, SDS-PAGE under reducing conditions Oryctolagus cuniculus
? x * 65000, rabbit, active form, SDS-PAGE under reducing conditions Oryctolagus cuniculus