Application | Comment | Organism |
---|---|---|
diagnostics | MMP-7 is a potential biomarker of intrinsic cisplatin sensitivity, ICS, which cisplatin treatment outcome in cancer therapy for advanced head and neck squamous cell carcinomas, overview | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fibronectin 1 | fibronectin 1, interacts with MMP-7 | Homo sapiens | |
TIMP3 | tissue inhibitor of metalloproteinase-3, interacts with MMP-7 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | MMP-7 interacts with insulin-like growth factor binding protein 5, inhibitor of metalloproteinase-3, fibronectin 1, and TFPI | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
salivary duct cancer cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | MMP-7 interacts with insulin-like growth factor binding protein 5, inhibitor of metalloproteinase-3, fibronectin 1, and TFPI | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Matrix metalloproteinase-7 | - |
Homo sapiens |
MMP-7 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | MMP-7 is a key regulator of cisplatin resistance in cells of head and neck squamous cell carcinomas, overview | Homo sapiens |