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Literature summary for 3.4.24.23 extracted from

  • Chiao, Y.A.; Zamilpa, R.; Lopez, E.F.; Dai, Q.; Escobar, G.P.; Hakala, K.; Weintraub, S.T.; Lindsey, M.L.
    In vivo matrix metalloproteinase-7 substrates identified in the left ventricle post-myocardial infarction using proteomics (2010), J. Proteome Res., 9, 2649-2657.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information construction of MMP-7 null mice that show lower levels of full-length peroxiredoxin-1 and -2 and higher levels of the full-length peroxiredoxin-3, suggesting MMP-7 deletion may also indirectly regulate protein levels through nonenzymatic mechanisms. Null mice also show reduced fibronectin and tenascin-C fragment generation, which is restored by exogenous administration of MMP-7 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fibronectin + H2O Mus musculus production of protein fragments ?
-
?
tenascin-C + H2O Mus musculus production of protein fragments ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
male C57/BL6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Mus musculus
-
left ventricle
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibronectin + H2O production of protein fragments Mus musculus ?
-
?
tenascin-C + H2O production of protein fragments Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
Matrix metalloproteinase-7
-
Mus musculus
MMP-7
-
Mus musculus

General Information

General Information Comment Organism
physiological function MMP-7 deletion improves survival after myocardial infarction Mus musculus