Literature summary for 3.4.24.23 extracted from

Dunn, K.M.; Lee, P.K.; Wilson, C.M.; Iida, J.; Wasiluk, K.R.; Hugger, M.; McCarthy, J.B.
Inhibition of hyaluronan synthases decreases matrix metalloproteinase-7 (MMP-7) expression and activity (2009), Surgery, 145, 322-329.

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Cloned(Commentary)

Cloned (Comment)	Organism
semi- and quantitative MMP-7 expression analysis in SW620 cells	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
GM6001	-	Homo sapiens
additional information	inhibition of hyaluronan synthases HAS2 and HAS3 highly decreases MMP-7 expression and activity in SW620 cells	Homo sapiens
TIMP-2	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P09237	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
SW-620 cell	colon cancer cell line, high levels of MMP-7	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
Matrix metalloproteinase-7	-	Homo sapiens
MMP-7	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	inhibition of hyaluronan synthases HAS2 and HAS3 highly decreases MMP-7 expression and activity in SW620 cells	down

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Release 2023.1 (January 2023)