Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.23 extracted from

  • Swee, M.; Wilson, C.L.; Wang, Y.; McGuire, J.K.; Parks, W.C.
    Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients (2008), J. Leukoc. Biol., 83, 1404-1412.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.23

Activating Compound

Activating Compound Comment Organism Structure
additional information MMP7 is induced upon mucosal injury in several tissues, e.g. in colon mucosa, which can be lethal to mice, overview Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information enzyme-deficient MMP7-/- mice show a lower mortality rate compared to wild-type mice in case of colon mucosal injury and inflammation, while neutrophil influx is similar in both cases, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus MMP7 is induced upon mucosal injury in several tissues, e.g. in colon mucosa, which can be lethal to mice, enzyme-deficient mice show a much lower mortality rate compared to wild-type mice, overview ?
-
 ?
additional information Mus musculus C57BL/6 MMP7 is induced upon mucosal injury in several tissues, e.g. in colon mucosa, which can be lethal to mice, enzyme-deficient mice show a much lower mortality rate compared to wild-type mice, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q10738 C57BL/6 mice
-
Mus musculus C57BL/6 Q10738 C57BL/6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
colon MMP7 is induced upon mucosal injury in several tissues, e.g. in colon mucosa, overview Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information MMP7 is induced upon mucosal injury in several tissues, e.g. in colon mucosa, which can be lethal to mice, enzyme-deficient mice show a much lower mortality rate compared to wild-type mice, overview Mus musculus ?
-
 ?
additional information MMP7 is induced upon mucosal injury in several tissues, e.g. in colon mucosa, which can be lethal to mice, enzyme-deficient mice show a much lower mortality rate compared to wild-type mice, overview Mus musculus C57BL/6 ?
-
 ?

Synonyms

Synonyms Comment Organism
Matrix metalloproteinase 7
-
 Mus musculus
Matrix metalloproteinase-7
-
 Mus musculus
MMP7
-
 Mus musculus