Literature summary for 3.4.24.23 extracted from

Harrell, P.C.; McCawley, L.J.; Fingleton, B.; McIntyre, J.O.; Matrisian, L.M.
Proliferative effects of apical, but not basal, matrix metalloproteinase-7 activity in polarized MDCK cells (2005), Exp. Cell Res., 303, 308-320.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	secretion of enzyme both to basolateral and apical compartment. Enzyme protein is more abundant in basolateral compartment, but the activity is 2fold higher in apical compartment. Enzyme overexpression increases cell saturation density as a result of increased cell proliferation due to apical enzyme activity	Homo sapiens	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	expression in polarized MDCK cell and HCA-7 and Caco2 colon cancer cell lines	-

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Release 2023.1 (January 2023)