Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.23 extracted from

  • Miyamoto, S.; Yano, K.; Sugimoto, S.; Ishii, G.; Hasebe, T.; Endoh, Y.; Kodama, K.; Goya, M.; Chiba, T.; Ochiai, A.
    Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3 (2004), Cancer Res., 64, 665-671.
    View publication on PubMed
Search for more literature for 3.4.24.23

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
IGFBP-3 + H2O Homo sapiens i.e. insulin-like growth factor binding protein 3, proteolysis by enzyme plays a crucial role in regulating IGF-I bioavailability, thereby promoting cell survival ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 recombinant enzyme
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
IGFBP-3 + H2O i.e. insulin-like growth factor binding protein 3, proteolysis by enzyme plays a crucial role in regulating IGF-I bioavailability, thereby promoting cell survival Homo sapiens ?
-
 ?
IGFBP-3 + H2O i.e. insulin-like growth factor binding protein 3, hydrolysis leads to four major fragments. Cleavage sites include K144-I145 and R95-L96 Homo sapiens ?
-
 ?