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Literature summary for 3.4.24.22 extracted from

  • Deraz, E.M.; Kudo, Y.; Yoshida, M.; Obayashi, M.; Tsunematsu, T.; Tani, H.; Siriwardena, S.B.; Kiekhaee, M.R.; Qi, G.; Iizuka, S.; Ogawa, I.; Campisi, G.; Lo Muzio, L.; Abiko, Y.; Kikuchi, A.; Takata, T.
    MMP-10/stromelysin-2 promotes invasion of head and neck cancer (2011), PLoS ONE, 6, e25438.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
squamous cell carcinoma cell head and neck squamous cell carcinoma (HNSCC) Homo sapiens
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Synonyms

Synonyms Comment Organism
MMP-10
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens high expression of MMP-10 is frequently observed and is significantly correlated with the invasiveness and metastasis in head and neck squamous cell carcinoma cases up

General Information

General Information Comment Organism
malfunction ectopic overexpression of MMP-10 promotes the invasion of head and neck squamous cell carcinoma cells, and knockdown of MMP-10 suppressed the invasion of head and neck squamous cell carcinoma cells Homo sapiens
physiological function MMP-10 plays an important role in the invasion and metastasis of head and neck squamous cell carcinoma Homo sapiens