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Literature summary for 3.4.24.22 extracted from

  • Kaner, R.J.; Santiago, F.; Crystal, R.G.
    Up-regulation of alveolar macrophage matrix metalloproteinases in HIV1(+) smokers with early emphysema (2009), J. Leukoc. Biol., 86, 913-922.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression analysis Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Homo sapiens
-
-
extracellular matrix
-
Homo sapiens 31012
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fibronectin + H2O Homo sapiens
-
?
-
?
additional information Homo sapiens stromelysins are enzymatically active against proteoglycans, procollagenase, and fibronectin ?
-
?
procollagenase + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification MMP-10 is activated from a pro-MMP-10 form Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
epithelial lining fluid
-
Homo sapiens
-
lung alveolar mucosa stromelysin 2/MMP-10 expression is highest in the HIV1- and HIV1+ smokers with early emphysema, where it is significantly higher than in HIV1- healthy smokers, overview Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibronectin + H2O
-
Homo sapiens ?
-
?
additional information stromelysins are enzymatically active against proteoglycans, procollagenase, and fibronectin Homo sapiens ?
-
?
procollagenase + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
MMP-10
-
Homo sapiens