Cloned (Comment) | Organism |
---|---|
MMP-10 DNA and amino acid sequence determination and expression analysis in HUVECs, transcriptional regulation of MMP-10 by Ets transcription factors, overview | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | MMP-10 knockdown by siRNA | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P09238 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
umbilical vein endothelial cell | HUVEC, quantitative RT-PCR of MMPs, overview | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
MMP-10 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | PD98059 and SP600125, ERK and JNK inhibitors, respectively, repress VEGF-induced MMP-10 expression to mRNA expression levels lower than the basal expression of MMP-10 | down |
Homo sapiens | VEGF165 induces MMP-10 expression about 2fold. LY294002 inhibits VEGF-induced MMP-10 expression, indicating the involvement of PI3K in VEGF-induced MMP-10 expression | up |
General Information | Comment | Organism |
---|---|---|
malfunction | MMP-10 plays a critical role in VEGF-induced angiogenesis, overview | Homo sapiens |
additional information | transcriptional regulation of MMP-10 by Ets transcription factors | Homo sapiens |