Literature summary for 3.4.24.22 extracted from

Bertini, I.; Calderone, V.; Fragai, M.; Luchinat, C.; Mangani, S.; Terni, B.
Crystal structure of the catalytic domain of human matrix metalloproteinase 10 (2004), J. Mol. Biol., 336, 707-716.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
recombinant catalytic domain, in complex with inhibitor N-isobutyl-N-(4-methoxy-phenylsulfonyl)glycyl hydroxamic acid, i.e. NNGH. Comparison with structure of matrix metalloproteinase MMP-3	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
N-isobutyl-N-(4-methoxy-phenylsulfonyl)glycyl hydroxamic acid	i.e. NNGH, study of binding mode. Interaction of inhibitor with Zn1 atom and S1 subsite	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	catalytic domain, expression in Escherichia coli	-

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Release 2023.1 (January 2023)