Literature summary for 3.4.24.17 extracted from

Geurts, N.; Martens, E.; Van Aelst, I.; Proost, P.; Opdenakker, G.; Van den Steen, P.E.
Beta-hematin interaction with the hemopexin domain of gelatinase B/MMP-9 provokes autocatalytic processing of the propeptide, thereby priming activation by MMP-3 (2008), Biochemistry, 47, 2689-2699.

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Activating Compound

Activating Compound	Comment	Organism	Structure
beta-hematin	induces differential autocatalysis of the propeptide	Homo sapiens
hemin	induces differential autocatalysis of the propeptide	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
1,10-phenanthroline	-	Homo sapiens
EDTA	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)