Any feedback?
Literature summary for 3.4.24.17 extracted from
- Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor (1998), Biochemistry, 37, 14048-14056.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | important target for inhibitor design and synthesis because of the widespread implications in arthritis, cancer, and cardiovascular disease | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| hydroxamic acid inhibitor CGS 27023 | - |
Homo sapiens |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 57000 | - |
- |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | - |
Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MMP-3 | - |
Homo sapiens |
| stromelysin-1 | - |
Homo sapiens |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000013 | - |
hydroxamic acid inhibitor CGS 27023 | pH 6.8, 37°C | Homo sapiens | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
