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Literature summary for 3.4.24.14 extracted from

  • Prockop, D.L.; Sieron, A.L.; Li, S.W.
    Procollagen N-proteinase and procollagen C-proteinase. Two unusual metalloproteinases that are essential for procollagen processing probably have important roles in development and cell signaling (1998), Matrix Biol., 16, 399-408.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required for maximal activity Gallus gallus
Ca2+ required for maximal activity Bos taurus
Zn2+
-
Gallus gallus
Zn2+ protein contains Zn2+ binding sequence Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
procollagen I + H2O Gallus gallus
-
?
-
?
procollagen I + H2O Bos taurus
-
?
-
?
procollagen II + H2O Gallus gallus
-
?
-
?
procollagen II + H2O Bos taurus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
tendon
-
Gallus gallus
-
tendon
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
procollagen I + H2O not procollagen III Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O not procollagen III Bos taurus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O substrate must be in native state Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O substrate must be in native state Bos taurus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O
-
Gallus gallus ?
-
?
procollagen I + H2O
-
Bos taurus ?
-
?
procollagen II + H2O substrate must be in native state Gallus gallus pCCollagen II + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen II + H2O substrate must be in native state Bos taurus pCCollagen II + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen II + H2O
-
Gallus gallus ?
-
?
procollagen II + H2O
-
Bos taurus ?
-
?