Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.14 extracted from

  • Dombrowski, K.E.; Sheats, J.E.; Prockop, D.J.
    Iron-containing metallocenes as active site directed inhibitors of the proteinase that cleaves the NH2-terminal propeptides from type I procollagen (1986), Biochemistry, 25, 4302-4309.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
Gallus gallus
ferrocene derivatives
-
Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required for maximal activity Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
procollagen I + H2O Gallus gallus
-
?
-
?
procollagen II + H2O Gallus gallus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
procollagen I + H2O not procollagen III Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O not procollagen IV Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O
-
Gallus gallus ?
-
?
procollagen II + H2O
-
Gallus gallus pCCollagen II + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen II + H2O
-
Gallus gallus ?
-
?