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Literature summary for 3.4.24.12 extracted from
- Biosynthesis and secretion of the hatching enzyme during sea urchin embryogenesis (1990), J. Biol. Chem., 265, 8704-8711.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Strongylocentrotus purpuratus |  |
| reactive red 120 | - |
Strongylocentrotus purpuratus | |
| triazine dye | - |
Strongylocentrotus purpuratus | |
| Zn2+ | - |
Strongylocentrotus purpuratus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | required | Strongylocentrotus purpuratus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 33000 | - |
x * 33000, the enzyme is initially secreted as a 57000 Da protein, during purification it is converted to the 33000 Da form, SDS-PAGE | Strongylocentrotus purpuratus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| egg envelope | Strongylocentrotus purpuratus | proteolyzes the fertilization envelope, thereby allowing the embryo to hatch | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Strongylocentrotus purpuratus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryo | secretion by the blastula stage embryos during the 2-h period prior to hatching. The biosynthesis of the enzyme begins at the late morula/early blastula stage up to 6 h before secretion | Strongylocentrotus purpuratus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Strongylocentrotus purpuratus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| egg envelope | proteolyzes the fertilization envelope, thereby allowing the embryo to hatch | Strongylocentrotus purpuratus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 33000, the enzyme is initially secreted as a 57000 Da protein, during purification it is converted to the 33000 Da form, SDS-PAGE | Strongylocentrotus purpuratus |
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