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Literature summary for 3.4.24.11 extracted from

  • Hooper, N.M.; Kenny, A.J.; Turner, A.J.
    The metabolism of neuropeptides. Neurokinin A (substance K) is a substrate for endopeptidase-24.11 but not for peptidyl dipeptidase A (angiotensin-converting enzyme) (1985), Biochem. J., 231, 357-361.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
phosphoramidon
-
Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.133
-
His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
-
Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 + H2O i.e. neurokinin A, hydrolysis at two sites: Ser5-Phe6 and Gly8-Leu9 Sus scrofa His-Lys-Thr-Asp-Ser + Phe-Val-Gly + Leu-Met-NH2
-
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