Crystallization (Comment) | Organism |
---|---|
crystal structures of the soluble extracellular domain of neprilysin (residues 52-749) complexed with various potent and competitive inhibitors. Vapour diffusion with 25% PEG 3350, 200 mM ammonium sulfate, 100 mM bis-tris, pH 7.5 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
SW strain and C57B1/6J strain | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | neprilysin specific activity varies across mouse strains, with the highest activities in kidney and brain of SW mice. Aging is associated with a reduction in brain neprilysin specific activity in SW strain and C57B1/6J strain. The aging- and strain-dependent differences in neprilysin specific activity may explain, at least in part, the roles that aging and background mouse strain play in differential specification of the susceptibility towards the development of cerebral Abeta amyloidosis | Mus musculus | - |
kidney | neprilysin specific activity varies across mouse strains, with the highest activities in kidney and brain of SW mice | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
NEP | - |
Mus musculus |