Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CORM-2 | a tricarbonyldichlororuthenium (II) dimer, and a CO releasing molecule, inhibits the fibrinogenolytic effects of CatroxMP-II on coagulation kinetics in human plasma via CO | Crotalus atrox | |
EDTA | complete einhibition at 0.1 mM | Crotalus atrox | |
additional information | no inhibition by PMSF | Crotalus atrox |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | venom | Crotalus atrox | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | a metal-dependent a P-II class metalloproteinase from venom | Crotalus atrox |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Crotalus atrox | P34182 | - |
- |
Purification (Comment) | Organism |
---|---|
native enzyme from venom by anion exchange chromatography, dialysis, ultrafiltration, and gel filtration | Crotalus atrox |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Crotalus atrox | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 21000, SDS-PAGE | Crotalus atrox |
More | trypsin peptide mapping and mass spectrometric analysis | Crotalus atrox |
Synonyms | Comment | Organism |
---|---|---|
atrolysin-e | - |
Crotalus atrox |
CatroxMP-II | - |
Crotalus atrox |
fibrinogenolytic metalloproteinase | - |
Crotalus atrox |
snake venom metalloproteinase | - |
Crotalus atrox |
SVMP | - |
Crotalus atrox |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is regulated by heme | Crotalus atrox |
additional information | the snake venom metalloproteinase is heme-bound and CO-inhibited | Crotalus atrox |