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show all sequences of 3.4.23.B9

Amino acid preferences for a critical substrate binding subsite of retroviral proteases in type 1 cleavage sites

Bagossi, P.; Sperka, T.; Feher, A.; Kadas, J.; Zahuczky, G.; Miklossy, G.; Boross, P.; Toezser, J.; J. Virol. 79, 4213-4218 (2005)

Data extracted from this reference:

Metals/Ions
Metals/Ions
Commentary
Organism
Structure
NaCl
activates at 2 M
bovine leukemia virus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
bovine leukemia virus
-
BLV, belongs to the deltaretrovirus group
-
Purification (Commentary)
Commentary
Organism
from recombinant inclusion bodies
bovine leukemia virus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
study of influence of the P2 position residue on cleavage site specificity, overview
666190
bovine leukemia virus
?
-
-
-
-
Val-Ser-Gln-Ala-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Ala-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Asn-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Cys-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Cys-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Gly-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Gly-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Ile-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Ile-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Leu-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Leu-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Phe-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Phe-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Thr-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Thr-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Val-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Val-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Subunits
Subunits
Commentary
Organism
More
structure molecular modeling, S2 subsite sequence comparison
bovine leukemia virus
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
bovine leukemia virus
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5.6
-
assay at
bovine leukemia virus
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
NaCl
activates at 2 M
bovine leukemia virus
Purification (Commentary) (protein specific)
Commentary
Organism
from recombinant inclusion bodies
bovine leukemia virus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
study of influence of the P2 position residue on cleavage site specificity, overview
666190
bovine leukemia virus
?
-
-
-
-
Val-Ser-Gln-Ala-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Ala-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Asn-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Cys-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Cys-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Gly-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Gly-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Ile-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Ile-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Leu-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Leu-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Phe-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Phe-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Thr-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Thr-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Val-Ser-Gln-Val-Tyr-Pro-Ile-Val-Gln + H2O
-
666190
bovine leukemia virus
Val-Ser-Gln-Val-Tyr + Pro-Ile-Val-Gln
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
More
structure molecular modeling, S2 subsite sequence comparison
bovine leukemia virus
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
bovine leukemia virus
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5.6
-
assay at
bovine leukemia virus
Other publictions for EC 3.4.23.B9
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
693905
Eizert
Amino acid preferences of retr ...
bovine leukemia virus
J. Virol.
82
10111-10117
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
681171
Sperka
Bovine leukemia virus protease ...
bovine leukemia virus
J. Gen. Virol.
88
2052-2063
2007
2
-
-
-
4
-
14
43
-
-
-
-
-
6
-
-
-
-
-
-
-
-
40
-
1
-
-
44
1
-
-
-
14
-
-
2
-
-
-
-
4
-
-
14
14
43
-
-
-
-
-
-
-
-
-
-
-
-
40
-
1
-
-
44
1
-
-
-
-
-
-
-
-
-
666190
Bagossi
Amino acid preferences for a c ...
bovine leukemia virus
J. Virol.
79
4213-4218
2005
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
10
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
10
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
668796
Menard
-
Bovine leukemia virus retropep ...
bovine leukemia virus, bovine leukemia virus BLV
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds. )
1
169-171
2004
-
-
1
-
-
-
8
-
-
2
1
4
-
2
-
1
1
1
-
-
-
-
10
1
1
1
-
-
1
1
1
-
-
1
7
-
-
1
-
-
-
-
7
8
-
-
-
2
1
4
-
-
1
1
-
-
-
-
10
1
1
1
-
-
1
1
1
1
-
-
-
-
-
-
647867
Zahuczky
Cloning of the bovine leukemia ...
bovine leukemia virus
Biochim. Biophys. Acta
1478
1-8
2000
-
-
1
-
-
-
-
2
1
-
-
-
-
1
-
-
1
-
-
-
-
-
6
-
-
-
-
6
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
1
-
-
-
-
6
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
647864
Menard
Inhibition of activity of the ...
bovine leukemia virus
FEBS Lett.
346
268-272
1994
-
-
-
-
-
-
5
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
5
5
-
-
-
-
-
1
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
647865
Precigoux
Modelling, synthesis and biolo ...
bovine leukemia virus
FEBS Lett.
326
237-240
1993
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
647866
Menard
Bovine leukemia virus: purific ...
bovine leukemia virus
Virology
193
680-689
1993
-
-
-
-
-
-
1
-
-
2
1
-
-
3
-
-
1
-
-
-
1
-
1
1
1
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
2
1
-
-
-
-
1
-
-
1
-
1
1
1
1
-
-
1
1
-
-
-
-
-
-
-
-
647863
Rice N.R.; Stephens R.M.; Burny A.; Gilden R.V.
The gag and pol genes of bovin ...
bovine leukemia virus
Virology
142
357-377
1985
-
-
-
-
-
-
-
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-
1
-
-
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