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Literature summary for 3.4.23.B1 extracted from
- Cathepsin H and napsin A are active in the alveoli and increased in alveolar proteinosis (2008), Eur. Respir. J., 31, 1197-1204.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | studies on differentiation of primary from secondary effects in the pathogenesis of juvenile and adult forms of Pulmonary alveolar proteinosis | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O96009 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| bronchoalveolar system | bronchoalveolar lavage fluid (BALF), expression in | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
amounts and activities of napsin A studied by immunoblotting and specific substrate cleavage, general defect in napsin A expression or activity not observed as cause for abnormal surfactant accumulation in juvenile pulmonary alveolar proteinosis | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | napsin A expression analyzed in juvenile and adult forms of Pulmonary alveolar proteinosis (PALP) | Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| napsin A | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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