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Literature summary for 3.4.23.B1 extracted from

  • Brasch, F.; Ochs, M.; Kahne, T.; Guttentag, S.; Schauer-Vukasinovic, V.; Derrick, M.; Johnen, G.; Kapp, N.; Muller, K.M.; Richter, J.; Giller, T.; Hawgood, S.; Buhling, F.
    Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II-pneumocytes of the human lung (2003), J. Biol. Chem., 278, 49006-49014.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Homo sapiens
-
 peptides
-
 ?
precursor form of surfactant protein B + H2O Homo sapiens napsin A is involved in the N- and C-terminal processing of proSP-B in type II pneumocytes fragments of precursor form of surfactant protein B
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O96009
-
-

Source Tissue

Source Tissue Comment Organism Textmining
alveolar cell type II pneumocyte type II Homo sapiens
-
lung
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polypeptide + H2O
-
 Homo sapiens peptides
-
 ?
precursor form of surfactant protein B + H2O napsin A is involved in the N- and C-terminal processing of proSP-B in type II pneumocytes Homo sapiens fragments of precursor form of surfactant protein B
-
 ?
precursor form of surfactant protein B + H2O proSP-B, 42 kDa protein, critical component of pulmonary surfactant, several cleavage sites in the N-and C-terminus, 1 cleavage site in the mature protein part Homo sapiens fragments of precursor form of surfactant protein B 3 processing products ?