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Literature summary for 3.4.23.52 extracted from

  • Szabo, Z.; Albers, S.V.; Driessen, A.J.
    Active-site residues in the type IV prepilin peptidase homologue PibD from the archaeon Sulfolobus solfataricus (2006), J. Bacteriol., 188, 1437-1443.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
D157A the activity level of the mutant is comparable to that of the wild type enzyme Saccharolobus solfataricus
D173A the activity level of the mutant is comparable to that of the wild type enzyme Saccharolobus solfataricus
D180A the activity level of the mutant is comparable to that of the wild type enzyme Saccharolobus solfataricus
D187A the mutant shows an apparent reduction in activity Saccharolobus solfataricus
D187A/D188A the mutant does not cleave preflagellin Saccharolobus solfataricus
D188A the mutant shows about wild type activity Saccharolobus solfataricus
D207N the activity level of the mutant is comparable to that of the wild type enzyme Saccharolobus solfataricus
D23A the mutant does not cleave preflagellin Saccharolobus solfataricus
D30A the activity level of the mutant is comparable to that of the wild type enzyme Saccharolobus solfataricus
D80A the mutant does not cleave preflagellin Saccharolobus solfataricus

Inhibitors

Inhibitors Comment Organism Structure
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride
-
Saccharolobus solfataricus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Saccharolobus solfataricus 16020
-

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q6IFS8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pre-glucose-binding protein + H2O
-
Saccharolobus solfataricus glucose-binding protein + ?
-
?
preflagellin + H2O most efficient substrate Saccharolobus solfataricus flagellin + ?
-
?

Synonyms

Synonyms Comment Organism
PibD
-
Saccharolobus solfataricus