Inhibitors | Comment | Organism | Structure |
---|---|---|---|
pepstatin A | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Mus musculus | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
CTSD | - |
Mus musculus |
pro-CtsD | proenzyme | Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | enzyme expression is upregulated in damaged tubular cells in nephrotoxic and ischemia reperfusion induced acute kidney injury. Enzyme expression is increased during acute tubular necrosis in transplanted kidneys | up |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme inhibition leads to an improvement in kidney function, a reduction in apoptosis and a decrease in tubular cell damage in kidneys with nephrotoxic or ischemia reperfusion-induced acute kidney injury | Mus musculus |
physiological function | the enzyme plays a role in apoptosis during acute kidney injury | Mus musculus |