Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
Cat D | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | the enzyme expression is significantly upregulated in response to oxygen-glucose deprivation/reperfusion exposure | up |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme suppression has an inhibitory effect on cell apoptosis and the expression of proapoptotic proteins | Mus musculus |
physiological function | the enzyme is involved in the oxygen and glucose deprivation/reperfusion-induced apoptosis of astrocytes. Enzyme overexpression enhances cell apoptosis and the levels of apoptogenic proteins, including Bax and caspase-3 | Mus musculus |