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Literature summary for 3.4.23.5 extracted from

  • van der Hilst, J.C.; Kluve-Beckerman, B.; van der Meer, J.W.; Simon, A.
    Cathepsin D activity protects against development of type AA amyloid fibrils (2009), Eur. J. Clin. Invest., 39, 412-416.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
pepstatin A cathepsin D inhibitor Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
Homo sapiens 5764
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mononuclear cell
-
Homo sapiens
-
PBMC cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
serum amyloid A protein + H2O
-
Homo sapiens ?
-
?

General Information

General Information Comment Organism
physiological function cathepsin D activity protects against development of type AA amyloid fibrils Homo sapiens