Literature summary for 3.4.23.5 extracted from

Lou, X.; Xiao, T.; Zhao, K.; Wang, H.; Zheng, H.; Lin, D.; Lu, Y.; Gao, Y.; Cheng, S.; Liu, S.; Xu, N.
Cathepsin D is secreted from M-BE cells: its potential role as a biomarker of lung cancer (2007), J. Proteome Res., 6, 1083-1092.

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Application

Application	Comment	Organism
medicine	cathepsin D might serve as a biomarker for lung cancer	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bronchial epithelial cell line	in M-BE, a SV40T-transformed human bronchial epithelial cell line with phenotypic features of early tumorigenesis, it is shown by 2-DE/MALDI-TOF that cathepsin D among 23 other proteins is up-regulated	Homo sapiens	-
additional information	using a tissue microarray it is shown that the cathepsin D expression levels in squamous cell carcinoma tissues is significantly higher than those in normal donors	Homo sapiens	-
plasma	cathepsin D protein is over-expressed in plasma of 36 (out of 104) patients with lung squamous cell carcinoma	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
cathepsin D	-	Homo sapiens

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Release 2023.1 (January 2023)