Activating Compound | Comment | Organism | Structure |
---|---|---|---|
lipopolysaccharides | required for activity, protein-lipid interactions, overview | Escherichia coli |
Crystallization (Comment) | Organism |
---|---|
PDB 1I78 crystal structure analysis with reversal of mutations A99S, K261G, and G217K required for crystallization | Escherichia coli |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
outer membrane | dimyristoylphosphatidylcholine lipid bilayer embedded beta-barrel | Escherichia coli | 19867 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
Has a virtual requirement for Arg in the P1 position and a slightly less stringent preference for this residue in the P1' position, which can also contain Lys, Gly or Val. | active site structure, catalytic residues are Asp210 an His212, molecular dynamic simulations reveal substrate binding structure and structural requirements for the catalytic mechanism | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Ala-L-Arg-L-Arg-L-Ala + H2O | model peptide substrate | Escherichia coli | L-Ala-L-Arg + L-Arg-L-Ala | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | conformational flexibility of the outer membrane embedded enzyme, molecular dynamic simulation, overview | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
ompT | - |
Escherichia coli |