Crystallization (Comment) | Organism |
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evolutionary trace analysis identifies group-specific residues in the ligand binding sites of BACE1, and BACE2, EC 3.4.23.45.The residues are Pro70, Ile110, Ile126, andAsn233 of BACE1 substituting Lys86, Leu126, Leu142, and Leu246 of BACE2, respectively.These group-specific residues would be the reason for cleavage site selectivity in BACE1 and BACE2 biological function | Homo sapiens |
Organism | UniProt | Comment | Textmining |
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Homo sapiens | P56817 | - |
- |