Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6,7-furano-5,8a-dimethoxy hydrocoumaric acid methyl ester | inhibits 57.2% of the BACE1 activity at a concentration of 1 mM | Homo sapiens | |
6,7-furano-5-methoxy hydrocoumaric acid | - |
Homo sapiens | |
6,7-furano-5-methoxy hydrocoumaric acid methyl ester | - |
Homo sapiens | |
6,7-furano-8,8a-dimethoxy hydrocoumaric acid methyl ester | inhibits 48.3% of the BACE1 activity at a concentration of 1 mM | Homo sapiens | |
6,7-furano-8-methoxy hydrocoumaric acid | - |
Homo sapiens | |
6,7-furano-8-methoxy hydrocoumaric acid methyl ester | inhibits 36.4% of the BACE1 activity at a concentration of 1 mM | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
rhodamine-EVNLDAEFK-quencher + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BACE1 | - |
Homo sapiens |
beta-secretase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.64 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | 6,7-furano-5,8a-dimethoxy hydrocoumaric acid methyl ester |