Application | Comment | Organism |
---|---|---|
medicine | BACE1 is potential drug target for the treatment of Alzheimers disease and Notch-driven cancer types | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-((1S,2R)-1-benzyl-3-cyclopropylamino-2-hydroxy-propyl)-5-(methanesulfonyl-methyl-amino)-N'-((R)-1-phenyl-ethyl)-isophthalamide | beta-secretase inhibitor IV | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
amyloid precursor protein + H2O | Homo sapiens | - |
fragments of amyloid precursor protein | - |
? | |
Klotho protein + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
amyloid precursor protein + H2O | - |
Homo sapiens | fragments of amyloid precursor protein | - |
? | |
Klotho protein + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BACE1 | - |
Homo sapiens |
beta-APP cleaving enzyme 1 | - |
Homo sapiens |
beta-secretase | - |
Homo sapiens |