Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-amyloid precursor protein + H2O | Cricetulus griseus | the loss of Niemann-Pick type C1 increases beta-secretase cleavage of beta-amyloid precursor protein | fragments of amyloid precursor protein | - |
? | |
beta-amyloid precursor protein + H2O | Cricetulus griseus | - |
fragments of beta-amyloid precursor protein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cricetulus griseus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
CHO cell | - |
Cricetulus griseus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-amyloid precursor protein + H2O | the loss of Niemann-Pick type C1 increases beta-secretase cleavage of beta-amyloid precursor protein | Cricetulus griseus | fragments of amyloid precursor protein | - |
? | |
beta-amyloid precursor protein + H2O | - |
Cricetulus griseus | fragments of beta-amyloid precursor protein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BACE-1 | - |
Cricetulus griseus |
BACE1 | - |
Cricetulus griseus |
beta-secretase | - |
Cricetulus griseus |
Organism | Comment | Expression |
---|---|---|
Cricetulus griseus | the loss of Niemann-Pick type C1 affects beta-amyloid generation by increasing beta-secretase cleavage | up |