Literature summary for 3.4.23.46 extracted from

von Arnim, C.A.; Kinoshita, A.; Peltan, I.D.; Tangredi, M.M.; Herl, L.; Lee, B.M.; Spoelgen, R.; Hshieh, T.T.; Ranganathan, S.; Battey, F.D.; Liu, C.X.; Bacskai, B.J.; Sever, S.; Irizarry, M.C.; Strickland, D.K.; Hyman, B.T.
The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate (2005), J. Biol. Chem., 280, 17777-17785.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cell surface	close interaction between BACE and low density lipoprotein receptor-related protein on the cell surface	Homo sapiens	9986	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
amyloid precursor protein + H2O	-	Homo sapiens	?	-	?
low density lipoprotein receptor-related protein + H2O	-	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
BACE	-	Homo sapiens

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Release 2023.1 (January 2023)