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Literature summary for 3.4.23.40 extracted from

  • Wu, H.; Castanheira, P.; Faro, C.; Tang, J.
    Cardosin A endocytosis mediated by integrin leads to lysosome leakage and apoptosis of epithelial cells (2019), Proteins, 87, 502-511 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Cynara cardunculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
carpel
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Cynara cardunculus
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Synonyms

Synonyms Comment Organism
cardosin A
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Cynara cardunculus

General Information

General Information Comment Organism
physiological function epithelial A549 cell-bound cardosin A is internalized to endosomes and lysosomes and triggers the permeability of lysosomal membrane leading to apoptosis of the epithelial cells. The enzyme may have a defensive function against the ingestion of cardoon flowers by human, insects, and other herbivores Cynara cardunculus