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Literature summary for 3.4.23.40 extracted from
- Aspartic proteinase from barley grains is related to mammalian lysosomal cathepsin D (1992), Planta, 186, 317-323.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| H-256 | substrate-analog inhibitor for cathepsin D | Hordeum vulgare |  |
| H-261 | substrate-analog inhibitor for cathepsin D | Hordeum vulgare | |
| L363 564 | substrate-analog inhibitor for cathepsin D | Hordeum vulgare | |
| lactoyl-pepstatin | - |
Hordeum vulgare | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 11000 | - |
1 * 32000 + 1 * 16000 (48-kDa aspartic proteinase, precursor of the 40-k-Da aspartic proteinase), 1 * 29000 + 1 * 11000 (40-k-Da aspartic proteinase), SDS-PAGE | Hordeum vulgare |
| 16000 | - |
1 * 32000 + 1 * 16000 (48-kDa aspartic proteinase, precursor of the 40-k-Da aspartic proteinase), 1 * 29000 + 1 * 11000 (40-k-Da aspartic proteinase), SDS-PAGE | Hordeum vulgare |
| 29000 | - |
1 * 32000 + 1 * 16000 (48-kDa aspartic proteinase, precursor of the 40-k-Da aspartic proteinase), 1 * 29000 + 1 * 11000 (40-k-Da aspartic proteinase), SDS-PAGE | Hordeum vulgare |
| 32000 | - |
1 * 32000 + 1 * 16000 (48-kDa aspartic proteinase, precursor of the 40-k-Da aspartic proteinase), 1 * 29000 + 1 * 11000 (40-k-Da aspartic proteinase), SDS-PAGE | Hordeum vulgare |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Hordeum vulgare | - |
L. Cv. Kustaa, barley | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Hordeum vulgare |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| seed | - |
Hordeum vulgare | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | no hydrolysis of denatured alpha-hordothionin | Hordeum vulgare | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 1 * 32000 + 1 * 16000 (48-kDa aspartic proteinase, precursor of the 40-k-Da aspartic proteinase), 1 * 29000 + 1 * 11000 (40-k-Da aspartic proteinase), SDS-PAGE | Hordeum vulgare |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 3.5 | 3.9 | substrate hemoglobin | Hordeum vulgare |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 4 | - |
inactive above | Hordeum vulgare |
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Release 2023.1 (January 2023)
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